February 24, 2026
Hemanth Kapa '27 will present Enhancing Tomographic Membrane Analysis: A GUI for Surface Morphometrics Pipeline. Pizza provided and everyone welcome.
Membrane shape and organization are central to cellular function, influencing protein interactions, organelle communication, and signaling. Cryo-electron tomography (cryo-ET) enables high-resolution 3D visualization of membranes in their native state, but quantitative analysis remains technically demanding. The surface morphometrics pipeline addresses this by measuring membrane properties such as curvature, spacing, and orientation from cryo-ET data. To improve accessibility, we are developing a graphical user interface (GUI) built on python based interactive viewer Napari that streamlines the workflow. The interface includes a configuration editor, integrated visualization of segmentation and quantification data, and a Docker-packaged backend for reproducibility across computing environments. This tool makes advanced membrane ultrastructure analysis more accessible to the broader research community.
Further information
- Location: Tome 115
- Time: 12:00 pm - 1:00 pm
- Cost: Free