on sabbatical Spring 2016
Rector North Room 1304
His research interests center on the biology of cancer, in particular leukemia, and the mechanisms by which cancer cells might be reprogrammed to either behave normally or self destruct. He and his students use genomic, proteomic and bioinformatic methods to explore changes in gene expression that distinguish cancer cells from normal cells. His teaching interests included genetics, molecular genetics, bioinformatics and the biology of cancer.
BIOL 316 Genomics/Proteomics/Bioinforma
The genome contains all the information required for the construction and operation of an organism. Selective utilization of the genome determines the transcriptome, which directs the creation of a proteome that is cell-type and condition specific. Today, molecular biologists are able to study whole genomes, transcriptomes, and proteomes allowing for an integrative analysis of living systems. This course will explore these genomic and proteomic techniques and their many applications. Central to these molecular methods are computational tools that facilitate the analysis of the large data sets generated. A variety of bioinformatics approaches will be explored through implementation of student designed, hypothesis-driven, research projects employing existing datasets. Six hours classroom per week. Prerequisites: 216 or permission of instructor.
BIOL 425 The Biology of Cancer w/lab
Cancer is a genetic disorder that affects some 10 million people worldwide. In the United States, cancer is a close second to heart disease as the leading cause of death. This course will examine the molecular basis of cancer including the genes and signaling pathways involved in malignant transformation and the physiological consequences of uncontrolled cell growth. Current methods in cancer research and recent advances in cancer treatment will also be discussed. Specific topics covered will include: oncogenes and tumor suppressor genes, oncogenic mutation, tumor viruses, apoptosis, angiogenesis, metastasis, tumor immunology, radiation therapy, chemotherapy, and biological therapy. Six hours classroom/laboratory a week. Prerequisite: One of the following: 216, 313, 316, 318, 326, 327, 380, or permission of the instructor.
BCMB 560 Stu/Faculty Collaborative Rsch
Student/Faculty Collaborative Research allows a student to conduct original research in close partnership with faculty collaborator(s). The project should be designed as an investigation yielding novel results that contribute to the area of study. With the faculty collaborator(s), students will develop the project and participate in all aspects fo the reasearch. It is expected that the faculty member will work closely with the student for at least half of the time the student is pursuing the research. The final project must be presented to the faculty collaborator(s) no later than one week prior to the end of the evaluation period. The course will typically earn one half or one full course credit per semester.